Amalgamated data for drug is current as of 2017/10/19 23:29:39

Cancer drug prices rising far faster than inflation

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Cancer drug prices rising far faster than inflation

(Reuters Health) - The prices of injectable cancer drugs - even older medicines around since the 1990s - are increasing at a rate far higher than inflation, researchers report in the Journal of Clinical Oncology.

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Drug Rehab - Addiction Healing Centre

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Drug Rehab - Addiction Healing Centre

Drug Rehab - Addiction Healing Centre

Find out more at addictionhealingcentre.ca

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5627007733

Photo by 12836528@N00

"A Hippie Doctor in the 80s", San Francisco Examiner, June 1987, 3 of 3

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"A Hippie Doctor in the 80s", San Francisco Examiner, June 1987, 3 of 3

"A Hippie Doctor in the 80s", San Francisco Examiner, June 1987, 3 of 3

Injecting drug use continues in older drug users too

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Injecting drug use continues in older drug users too

Rao and Roche note that the number of people aged over 50 who have substance misuse problems is rising globally across a range of settings.1 This rise also applies to people who inject drugs, at...

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Injecting drug use continues in older drug users too

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Injecting drug use continues in older drug users too

Rao and Roche note that the number of people aged over 50 who have substance misuse problems is rising globally across a range of settings.1 This rise also applies to people who inject drugs, at...

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"Summer of Love 20 Years Later", San Francisco Chronicle, April 1987, 10 of 14

San Francisco Public Library Branch Archives posted a photo:

"Summer of Love 20 Years Later", San Francisco Chronicle, April 1987, 10 of 14

"Summer of Love 20 Years Later", San Francisco Chronicle, April 1987, 10 of 14

"A Hippie Doctor in the 80s", San Francisco Examiner, June 1987, 2 of 3

San Francisco Public Library Branch Archives posted a photo:

"A Hippie Doctor in the 80s", San Francisco Examiner, June 1987, 2 of 3

"A Hippie Doctor in the 80s", San Francisco Examiner, June 1987, 2 of 3

Celgene abandons Crohn's disease drug trials

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Celgene abandons Crohn's disease drug trials

(Reuters) - Celgene Corp said on Thursday it would stop two studies of its drug for an inflammatory bowel disease and would not begin a third, following a recommendation by a data monitoring committee.

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U.S. FDA panel backs approval of Novo Nordisk diabetes drug

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U.S. FDA panel backs approval of Novo Nordisk diabetes drug

WASHINGTON (Reuters) - Novo Nordisk A/S's new diabetes drug semaglutide is effective, reasonably safe and should be approved, an advisory panel to the U.S. Food and Drug Administration concluded on Wednesday.

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Rather toxic

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Rather toxic

Fly agarics resp. fly amanitas (Amanita muscaria) in a forest near the village of Mosbach, Franconia (Bavaria)

Some background information:

Amanita muscaria, commonly known as the fly agaric or fly amanita, is a mushroom and psychoactive basidiomycete fungus, one of many in the genus Amanita. Native throughout the temperate and boreal regions of the Northern Hemisphere, Amanita muscaria has been unintentionally introduced to many countries in the Southern Hemisphere, generally as a symbiont with pine and birch plantations, and is now a true cosmopolitan species. It associates with various deciduous and coniferous trees.

Arguably the most iconic toadstool species, the fly agaric is a large white-gilled, white-spotted, usually red mushroom, and is one of the most recognisable and widely encountered in popular culture. Several subspecies with differing cap colour have been recognised, including the brown regalis (often considered a separate species), the yellow-orange flavivolvata, guessowii, formosa, and the pinkish persicina. Genetic studies published in 2006 and 2008 show several sharply delineated clades that may represent separate species.

Although classified as poisonous, reports of human deaths resulting from its ingestion are extremely rare. After parboiling—which weakens its toxicity and breaks down the mushroom's psychoactive substances—it is eaten in parts of Europe, Asia, and North America. Amanita muscaria is noted for its hallucinogenic properties, with its main psychoactive constituent being the compound muscimol. The mushroom was used as an intoxicant and entheogen by the peoples of Siberia, and has a religious significance in these cultures. There has been much speculation on possible traditional use of this mushroom as an intoxicant in other places such as the Middle East, Eurasia, North America, and Scandinavia.

A large, conspicuous mushroom, amanita muscaria is generally common and numerous where it grows, and is often found in groups with basidiocarps in all stages of development. Fly agaric fruiting bodies emerge from the soil looking like white eggs. After emerging from the ground, the cap is covered with numerous small white to yellow pyramid-shaped warts. These are remnants of the universal veil, a membrane that encloses the entire mushroom when it is still very young. Dissecting the mushroom at this stage will reveal a characteristic yellowish layer of skin under the veil; this is helpful in identification. As the fungus grows, the red colour appears through the broken veil and the warts become less prominent; they do not change in size, but are reduced relative to the expanding skin area. The cap changes from globose to hemispherical, and finally to plate-like and flat in mature specimens. Fully grown, the bright red cap is usually around 8 to 20 cm in diameter (3 to 8 in), although larger specimens have been found. The red colour may fade after rain and in older mushrooms.

The free gills are white, as is the spore print. The stipe is white too, 5 to 20 cm high (2.0 to 7.9 in) by 1 to 2 cm wide (0.5 to 1 in), and has the slightly brittle, fibrous texture typical of many large mushrooms. At the base is a bulb that bears universal veil remnants in the form of two to four distinct rings or ruffs. Between the basal universal veil remnants and gills are remnants of the partial veil (which covers the gills during development) in the form of a white ring. It can be quite wide and flaccid with age. There is generally no associated smell other than a mild earthiness.

Amanita muscaria is a cosmopolitan mushroom, native to conifer and deciduous woodlands throughout the temperate and boreal regions of the Northern Hemisphere,[26] including higher elevations of warmer latitudes in regions such as Hindu Kush, the Mediterranean and also Central America. Fruiting occurs in summer and autumn across Europe and most of North America. This species is often found in similar locations to Boletus edulis, and may appear in fairy rings. Conveyed with pine seedlings, it has been widely transported into the southern hemisphere, including Australia, New Zealand, South Africa and South America.

Amanita muscaria poisoning has occurred in young children and in people who ingested the mushrooms for a hallucinogenic experience. Amanita muscaria contains several biologically active agents, at least one of which, muscimol, is known to be psychoactive. Ibotenic acid, a neurotoxin, serves as a prodrug to muscimol, with approximately 10–20% converting to muscimol after ingestion. An active dose in adults is approximately 6 mg muscimol or 30 to 60 mg ibotenic acid. This is typically about the amount found in one cap of Amanita muscaria. The amount and ratio of chemical compounds per mushroom varies widely from region to region and season to season, which can further confuse the issue. Spring and summer mushrooms have been reported to contain up to 10 times more ibotenic acid and muscimol than autumn fruitings.

A fatal dose has been calculated as 15 caps. Deaths from this fungus Amanita muscaria have been reported in historical journal articles and newspaper reports, but with modern medical treatment, fatal poisoning from ingesting this mushroom is extremely rare. Many older books list Amanita muscaria as "deadly", but this is an error that implies the mushroom is more toxic than it is. The vast majority (90% or more) of mushroom poisoning deaths are from eating the greenish to yellowish "death cap", or perhaps even one of the three white Amanita species which are known as destroying angels, Amanita virosa, Amanita bisporigera and Amanita ocreata.

Fly agarics are known for the unpredictability of their effects. Depending on habitat and the amount ingested per body weight, effects can range from nausea and twitching to drowsiness, cholinergic crisis-like effects (low blood pressure, sweating and salivation), auditory and visual distortions, mood changes, euphoria, relaxation, ataxia, and loss of equilibrium.

In cases of serious poisoning the mushroom causes delirium, somewhat similar in effect to anticholinergic poisoning, characterised by bouts of marked agitation with confusion, hallucinations, and irritability followed by periods of central nervous system depression. Seizures and coma may also occur in severe poisonings. Symptoms typically appear after around 30 to 90 minutes and peak within three hours, but certain effects can last for several days. In the majority of cases recovery is complete within 12 to 24 hours. The effect is highly variable between individuals, with similar doses potentially causing quite different reactions. Some people suffering intoxication have exhibited headaches up to ten hours afterwards. Retrograde amnesia and somnolence can result following recovery.

The wide range of psychoactive effects can be variously described as depressant, sedative-hypnotic, psychedelic, dissociative, and deliriant. Paradoxical effects such as stimulation may occur however. Perceptual phenomena such as synesthesia, macropsia, and micropsia may occur. Some users report lucid dreaming under the influence of its hypnotic effects. Unlike Psilocybe cubensis, Amanita muscaria cannot be commercially cultivated, due to its mycorrhizal relationship with the roots of pine trees.

Celgene to stop testing Crohn's drug, shares drop

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Celgene to stop testing Crohn's drug, shares drop

(Reuters) - Celgene Corp said it would abandon testing a drug to treat Crohn's disease, an inflammatory bowel disease, following a risk-benefit analysis by a data monitoring committee, in a major setback to the drugmaker's pipeline.

from Reuters: Health News ift.tt/2zmGJPo
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Cách mua thuốc trị sẹo lõm lâu năm trên mặt hiệu quả tốt nhất

i_miss_you_0409 posted a photo:

Cách mua thuốc trị sẹo lõm lâu năm trên mặt hiệu quả tốt nhất

Xem black friday cell phone deals 2015 và black friday tablet deals và wii u black friday 2015 và tại đây

Novo Nordisk takes aim at Eli Lilly with U.S. backing of new diabetes drug

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Novo Nordisk takes aim at Eli Lilly with U.S. backing of new diabetes drug

WASHINGTON/COPENHAGEN (Reuters) - Denmark's Novo Nordisk will take aim at Eli Lilly in the growing diabetes market after an advisory panel to the U.S. Food and Drug Administration (FDA) gave the green light to its semaglutide drug.

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Medical News Today: Colorectal cancer: New, less toxic drug target uncovered

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Medical News Today: Colorectal cancer: New, less toxic drug target uncovered

New research uncovers a novel, less toxic drug target for treating colorectal cancer, which currently affects approximately 135,000 people in the U.S.
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Pre-sex HIV drug 'no-brainer" for NHS

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Pre-sex HIV drug 'no-brainer" for NHS

Prep treatment could prevent a quarter of new HIV cases and save the NHS millions, experts calculate.
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Researchers watch in real time as fat-encased drug nanoparticles invade skin cells

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Researchers watch in real time as fat-encased drug nanoparticles invade skin cells

A new study describes the use of cutting-edge microscopy technology to visualize how liposomes escape from blood vessels into surrounding cells in a living mouse, offering clues that may help researchers design better drug delivery systems.
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Gladys Ng

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Gladys Ng

Treats! / Frederick's of Hollywood / Agent Provocateur (outtake - letting loose)

"Time for a Bex and a Good Lie Down"

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"Time for a Bex and a Good Lie Down"

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